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DMCM hydrochloride

CAS No. 1215833-62-7

DMCM hydrochloride( —— )

Catalog No. M10808 CAS No. 1215833-62-7

A potent benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DMCM hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.
  • Description
    A potent benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity; induces hypoalgesia on a wide range of assays, inhibits pain and learning in rats.
  • In Vitro
    ——
  • In Vivo
    DMCM has potent convulsant, proconvulsant and anxiogenic properties in vivo. DMCM (20-60 mg/kg; i.p.) produces modest anxiolytic-like effects in γ2I77 mice. Animal Model:Male γ2I77 mice Dosage:20 mg/kg and 60 mg/kg Administration:Injected i.p. Result:Produced modest anxiolytic-like effects.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GAT
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1215833-62-7
  • Formula Weight
    350.7968
  • Molecular Formula
    C17H19ClN2O4
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: ≥ 35 mg/mL
  • SMILES
    CCC1=C2C3=CC(=C(C=C3NC2=CN=C1C(=O)OC)OC)OC.Cl
  • Chemical Name
    9H-Pyrido[3,4-b]indole-3-carboxylic acid, 4-ethyl-6,7-dimethoxy-, methyl ester, hydrochloride (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Petersen EN. Eur J Pharmacol. 1983 Oct 14;94(1-2):117-24. 2. Contó MB, et al. Pharmacol Biochem Behav. 2005 Nov;82(3):417-26. 3. Sieve AN, et al. Psychopharmacology (Berl). 2001 Jan 1;153(2):180-90.
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